Treating Sepsis. When Seconds Matter.

A breakthrough, clinically proven technology designed for the immediate removal of bacteria from the bloodstream — delivering rapid infection control in critically ill patients.

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TRANSFORMATIVE APPROACH

A Direct Way to Treat Sepsis at Its Source

CycloPE® is an advanced blood purification therapy that treats sepsis by directly removing bacteria from the bloodstream. As blood passes through the device, harmful pathogens are captured while essential blood components remain intact and unaffected. Designed to integrate seamlessly with standard ICU systems, CycloPE® enables rapid bacterial clearance and supports faster patient recovery.

Direct Pathogen Removal

CycloPE® treats the source of the infection, bacteria

Rapid Response

The device can be used prior to pathogen identification, getting patients started on a therapy when time matters

Broad
Spectrum

CycloPE® is bacteria agnostic, removing drug-susceptible and drug resistance bacteria

Seamless Integration

The device has been designed to fit into existing hospital workflow and infrastructure

Targeted Therapy

CycloPE® targets and removes bacteria without changing the patients’ blood profile

Clinical
Data

Positive clinical data has shown safety, efficacy, and improvement in clinical markers tied to sepsis patient outcomes

Proven & Expert Team

Supported By Leading Partners

OUR STORY

Transforming the Fight Against Sepsis

Sepsis remains one of the leading causes of death in hospitals worldwide, with survival dependent on how quickly and effectively the infection is brought under control. Current treatment options are failing patients, with the rise of drug-resistance and emerging pathogens. PATH EX developed the CycloPE® device as an advanced blood purification therapy purpose-built to rapidly and selectively remove bacteria from the bloodstream. As the first extracorporeal technology specifically designed for targeted, high-efficiency bacterial removal, CycloPE® integrates seamlessly with existing ICU workflows, and can be used prior to pathogen identification. The device enables clinicians to make timely, effective treatment accessible to patients when every second counts.

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